Synthetic Biology
Systems Biology

Play the DNA factory game
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Synthetic Biology
Systems Biology

Keeping synthetic biology safe.
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Synthetic Biology
Systems Biology

Measuring gene expression in single cells.
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Synthetic Biology
Systems Biology

Designing synthetic DNA molecules.
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Synthetic Biology
Systems Biology

Optimizing gene synthesis
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Get our Standard Operating Procedures

Many people have expressed interest in learning more about the way we run the lab after the publication in PLoS Computational Biology of  ”If You Can’t Measure It, You Can’t Manage It“. Initially, we released them on this web site as individual posts for each SOP. That did not work too well. They took too […]

Releasing a list of synthetic biology blogs

I thought it might be useful to compile a list of Synthetic Biology blogs that can be used as alternative sources of information and perspectives complementing academic journals. This list was initially seed with contributions from Nathaniel Gore  and Devin Camenares. It was later expanded by submissions from the community. Do you know another SynBio blog that […]

Synthetic Biology Blogs

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I thought it might be useful to compile a list of Synthetic Biology blogs that can be used as alternative sources of information and perspectives complementing academic journals.  This list was prepared using contributions from Nathaniel Gore  and Devin Camenares. Do you know other SynBio blogs that should be added to the list? Use the comments below to suggest […]

ACS Synthetic Biology: this month articles

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ACS Synthetic Biology is progressively rapidly gaining traction in the synthetic biology community as a journal of choice for publishing papers relevant to our community. I thought it might be useful to identify articles that have  generated the most “buzz” in the last 30 days. Below are the articles that have been mentioned in social […]

ACS Synthetic Biology: all articles

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ACS Synthetic Biology is progressively rapidly gaining traction in the synthetic biology community as a journal of choice for publishing papers relevant to our community. I thought it might be useful to identify articles that have  generated the most “buzz”. Below are the articles that have been mentioned in social media at any time. Click on […]

A Guide for Communicating Synthetic Biology

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The Woodrow Wilson Center Synthetic Biology Project has just released a guide to help practitioners of synthetic biology communicate with different constituencies. Reading this document is cheap insurance against potential public relation disasters that may hurt not only you and your organization but our entire industry. We certainly do not want or need a major […]

Synthetic Biology: Patent or not Patent?

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Synthetic biology has emerged at the interface between life sciences and engineering. This has a resulted in a cultural divide regarding the status of intellectual property. Engineers have been advocating an open source model that has been spectacularly successful in computer science. Life scientists and specifically biotechnology companies have been defending the patenting of DNA […]

CRISPR-Cas9:Rational design of highly active sgRNAs

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A group led by David Root from the Broad Institute published a nice paper published in Nature Biotechnology (10.1038/nbt.3026) describing a predictive model of the sgRNA target sequence cleavage efficiency.  They created a pool of sgRNAs, tiling across all possible target sites of a panel of six endogenous mouse and three endogenous human genes and quantitatively […]

PLoS Looking for a Community Editor

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Do you eat, breathe and dream synthetic biology research? Like to blog and tweet? Read on to see if this opportunity is right for you. If you know the field and the literature from a researcher’s perspective and would like to work part-time as a PLOS Synthetic Biology Community Site Editor, you may be a […]

Toward a more efficient photosynthesis

A team lead by Maureen Hanson (Cornell University) has successfully replaced the native RUBISCO enzyme of tobacco cells with a faster RUBISCO of cyanobacterial origin. The RUBISCO enzyme is part of the photosynthetic pathway. It converts CO2 into sugar. Because of the complexity of this enzyme, this paper is a major landmark of plant biotechnology. […]